| | Nearly every major medical breakthrough over the past 50 years can be attributed to new discoveries that were made possible through meticulous biomedical research. Many diseases and conditions that previously took a heavy toll on patients in terms of both morbidity and mortality are now either treatable or preventable thanks in large part to painstaking research that expanded the frontiers of scientific knowledge and moved the most promising basic research developments into tangible health benefits through human clinical trails. Ongoing research is also the key that will open the door to additional major medical advances and breakthroughs in the future.
Our staff at Medifocus is committed to keeping our subscribers to the Medifocus Digest Alert on Parkinson's Disease abreast of the latest new research developments that have recently been published in the medical literature for this condition. In this issue of the Digest Alert, you will find a focused list of hand-picked journal article references that represent the latest advances in basic and clinical research for Parkinson's Disease. These articles represent the current state-of-the-art of the research that will hopefully lead to additional major advances and breakthroughs in the clinical management of Parkinson's Disease. You can access the summaries of each article referenced below by simply clicking on the article Title.
We will continue to update you with the latest scientific and clinical developments through the Medifocus Digest Alert on Parkinson's Disease every 3 months. Thank you for your ongoing subscription to this publication.
Elliot Jacob, Ph.D.
Vice-President - Content
Medifocus.com, Inc.
| Authors: | González-May CA, Barradas-Castillo MDR, Perera-Rios JH, Gallegos-Tintoré S, Pérez-Izquierdo O, Aranda-González II |
| Institution: | Facultad de Medicina, Universidad Autonoma de Yucatan, Centro, 97000, Merida, Yucatan, Mexico. Electronic address: irma.aranda@correo.uady.mx. | | Journal: | Nutr Res. 2024 Jan;121:39-50. doi: 10.1016/j.nutres.2023.10.004. Epub 2023 Nov 3. |
| Authors: | Hill DR, Huters AD, Towne TB, Reddy RE, Fogle JL, Voight EA, Kym PR |
| Institution: | | | Journal: | Chem Rev. 2023 Dec 13;123(23):13693-13712. doi: 10.1021/acs.chemrev.3c00479. Epub 2023 Nov 17. |
| Authors: | Degirmenci Y, Angelopoulou E, Georgakopoulou VE, Bougea A |
| Institution: | Department of Neurology, School of Medicine, Istanbul Health and Technology University, 34093 Istanbul, Turkey.; 1st Department of Neurology, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, 11528 Athens, Greece. | | Journal: | Medicina (Kaunas). 2023 Oct 1;59(10):1756. doi: 10.3390/medicina59101756. |
| Authors: | Malmir K, Ashrafganjooie M |
| Institution: | School of Rehabilitation, Physical Therapy Department, Tehran University of Medical Sciences, P. O. Box: 113635-1683, Tehran, Iran. kmalmir@tums.ac.ir.; School of Paramedical Sciences, Physical Therapy Department, Kerman University of Medical Sciences, Kerman, Iran. | | Journal: | Eur Geriatr Med. 2023 Dec;14(6):1273-1288. doi: 10.1007/s41999-023-00860-4. Epub 2023 Sep 12. |
| Authors: | Eslamian F, Dolatkhah N, Fallah L, Jahanjoo F, Toopchizadeh V, Talebi M |
| Institution: | Physical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.; Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. | | Journal: | Tremor Other Hyperkinet Mov (N Y). 2023 Aug 24;13:27. doi: 10.5334/tohm.773. eCollection 2023. |
| Authors: | Doggrell SA |
| Institution: | School of Pharmacy and Medical Sciences, Griffith University, Gold Coast Campus, Gold Coast, Queensland, Australia. | | Journal: | Expert Opin Drug Deliv. 2023 Jul-Dec;20(9):1189-1199. doi: 10.1080/17425247.2023.2253146. Epub 2023 Sep 10. |
| Authors: | Angelopoulou E, Stanitsa E, Karpodini CC, Bougea A, Kontaxopoulou D, Fragkiadaki S, Koros C, Georgakopoulou VE, Fotakopoulos G, Koutedakis Y, Piperi C, Papageorgiou SG |
| Institution: | 1st Department of Neurology, Medical School, National and Kapodistrian University of Athens, Eginition Hospital, 11528 Athens, Greece. | | Journal: | Medicina (Kaunas). 2023 Aug 12;59(8):1454. doi: 10.3390/medicina59081454. |
| Authors: | Campagnolo M, Emmi A, Biundo R, Fiorenzato E, Batzu L, Chaudhuri KR, Antonini A |
| Institution: | Parkinson's Disease and Movement Disorders Unit, Centre for Rare Neurological Diseases (ERN-RND), Department of Neuroscience, University of Padova, Padova, Italy. | | Journal: | Expert Opin Pharmacother. 2023 Sep-Dec;24(15):1693-1701. doi: 10.1080/14656566.2023.2240228. Epub 2023 Jul 26. |
| Authors: | Ciocca M, Seemungal BM, Tai YF |
| Institution: | Department of Brain Sciences, Imperial College London, London, UK. Electronic address: yen.tai@imperial.ac.uk. | | Journal: | Neuromodulation. 2023 Oct;26(7):1339-1361. doi: 10.1016/j.neurom.2023.06.003. Epub 2023 Jul 13. |
| Authors: | Grippe T, Chen R |
| Institution: | Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada; Division of Neurology, University of Toronto, Toronto, Ontario, Canada; Neuroscience Graduate Program, Federal University of Minas Gerais, Belo Horizonte, Brazil; Krembil Brain Institute, Toronto, Ontario, Canada; Divison of Neurology, Department of Medicine, University of Toronto, Canada.; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada; Krembil Brain Institute, Toronto, Ontario, Canada; Divison of Neurology, Department of Medicine, University of Toronto, Canada. Electronic address: robert.chen@uhn.ca. | | Journal: | Toxicon. 2023 Aug 15;232:107209. doi: 10.1016/j.toxicon.2023.107209. Epub 2023 Jul 8. |
| Authors: | Glover L, Dixon C, Kobylecki C, Eccles FJR |
| Institution: | Lancaster University, Health Innovation One, Sir John Fisher Drive, Lancaster University, Lancaster, UK. | | Journal: | Aging Ment Health. 2023 Nov-Dec;27(12):2420-2429. doi: 10.1080/13607863.2023.2227119. Epub 2023 Jun 24. |
| Authors: | Kim SW, Lee JH, Kim B, Yang G, Kim JU |
| Institution: | College of Korea Medicine, Woosuk University, Jeonju-si 54986, Republic of Korea. | | Journal: | Int J Mol Sci. 2023 May 16;24(10):8827. doi: 10.3390/ijms24108827. |
| Authors: | Li JA, Loevaas MB, Guan C, Goh L, Allen NE, Mak MKY, Lv J, Paul SS |
| Institution: | Discipline of Movement Sciences, School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. | | Journal: | Neurorehabil Neural Repair. 2023 May;37(5):328-352. doi: 10.1177/15459683231172752. Epub 2023 May 11. |
| Authors: | Jost WH, Kulisevsky J, LeWitt PA |
| Institution: | Parkinson-Klinik Ortenau, Kreuzbergstr. 12-16, 77709, Wolfach, Germany. w.jost@parkinson-klinik.de.; Wayne State University School of Medicine (Sastry Foundation Endowed Chair in Neurology and Henry Ford Hospital), Detroit, MI, 48201, USA. | | Journal: | J Neural Transm (Vienna). 2023 Jun;130(6):821-826. doi: 10.1007/s00702-023-02636-3. Epub 2023 Apr 23. |
| Authors: | Gardoni A, Sarasso E, Agosta F, Filippi M, Corbetta D |
| Institution: | Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Department of Rehabilitation and Functional Recovery, IRCCS San Raffaele Scientific Institute, Milan, Italy. corbetta.davide@hsr.it. | | Journal: | Neurol Sci. 2023 Aug;44(8):2667-2677. doi: 10.1007/s10072-023-06752-6. Epub 2023 Mar 25. |
| Authors: | Cavallieri F, Cury RG, Guimarães T, Fioravanti V, Grisanti S, Rossi J, Monfrini E, Zedde M, Di Fonzo A, Valzania F, Moro E |
| Institution: | Neurology Unit, Neuromotor & Rehabilitation Department, Azienda USL-IRCCS of Reggio Emilia, 42123 Reggio Emilia, Italy.; Division of Neurology, CHU of Grenoble, Grenoble Institute of Neurosciences, Grenoble Alpes University, 38700 Grenoble, France. | | Journal: | Cells. 2023 Feb 27;12(5):764. doi: 10.3390/cells12050764. |
| Authors: | López-Liria R, Vega-Tirado S, Valverde-Martínez MÁ, Calvache-Mateo A, Martínez-Martínez AM, Rocamora-Pérez P |
| Institution: | Health Research Centre, Department of Nursing, Physiotherapy and Medicine, University of Almeria, Carretera del Sacramento s/n, 04120 La Canada de San Urbano, Almeria, Spain. | | Journal: | Sensors (Basel). 2023 Feb 6;23(4):1817. doi: 10.3390/s23041817. |
| Authors: | Jabbari B, Comtesse SM |
| Institution: | Department of Neurology, Yale University School of Medicine, New Haven, CT 06519, USA.; Faculty of Medicine, Goethe University, 60590 Frankfurt am Main, Germany. | | Journal: | Toxins (Basel). 2023 Jan 17;15(2):81. doi: 10.3390/toxins15020081. |
| Authors: | Al-Kuraishy HM, Al-Gareeb AI, Alexiou A, Papadakis M, Alsayegh AA, Almohmadi NH, Saad HM, Batiha GE |
| Institution: | Department of Clinical Pharmacology and Medicine, College of Medicine, ALmustansiriyia University, Baghdad, Iraq.; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt. | | Journal: | Pharmacol Res Perspect. 2023 Apr;11(2):e01063. doi: 10.1002/prp2.1063. |
| Authors: | Hoseinipalangi Z, Pashazadeh Kan F, Hosseinifard H, Doustmehraban M, Masoumi M, Rafiei S, Barmayoon P, Ahmadi N, Dehnad A, Eshtod H, Asl MT, Sadat Hoseini B, Nasiri M, Arian M, Aghalou S, Ghashghaee A |
| Institution: | School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.; Social Determinants of |Health Research Center, Qazvin University of Medical Sciences, Qazvin, Islamic Republic of Iran. | | Journal: | East Mediterr Health J. 2023 Jan 19;29(1):63-70. doi: 10.26719/emhj.23.013. |
| Authors: | Maggi G, Vitale C, Cerciello F, Santangelo G |
| Institution: | Department of Psychology, University of Campania 'Luigi Vanvitelli', Caserta, Italy. Electronic address: gabriella.santangelo@unicampania.it. | | Journal: | Sleep Med Rev. 2023 Apr;68:101759. doi: 10.1016/j.smrv.2023.101759. Epub 2023 Jan 16. |
| Authors: | Bloem BR, Post E, Hall DA |
| Institution: | Department of Neurology, Centre of Expertise for Parkinson & Movement Disorders, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.; Department of Neurological Sciences, Rush University, Chicago, IL, USA. | | Journal: | Ann Neurol. 2023 Apr;93(4):681-685. doi: 10.1002/ana.26612. Epub 2023 Feb 9. |
| Authors: | Leite Silva ABR, Gonçalves de Oliveira RW, Diógenes GP, de Castro Aguiar MF, Sallem CC, Lima MPP, de Albuquerque Filho LB, Peixoto de Medeiros SD, Penido de Mendonça LL, de Santiago Filho PC, Nones DP, da Silva Cardoso PMM, Ribas MZ, Galvão SL, Gomes GF, Bezerra de Menezes AR, Dos Santos NL, Mororó VM, Duarte FS, Dos Santos JCC |
| Institution: | Centro Universitario Christus, UNICHRISTUS, Fortaleza, CE, Brazil.; Centro Universitario Christus, UNICHRISTUS, Fortaleza, CE, Brazil; Universidade Federal do Ceara, Fortaleza, CE, Brazil; Programa de Pos-graduacao em Ciencias Morfofuncionais, Departamento de Morfologia, Universidade Federal do Ceara, Fortaleza, CE, Brazil. Electronic address: julio.santos@alu.ufc.br. | | Journal: | Ageing Res Rev. 2023 Feb;84:101834. doi: 10.1016/j.arr.2022.101834. Epub 2022 Dec 26. |
| Authors: | Chen XT, Zhang Q, Wen SY, Chen FF, Zhou CQ |
| Institution: | Department of Neurology, Bishan Hospital of Chongqing Medical University, Chongqing, China. | | Journal: | Eur J Neurol. 2023 Mar;30(3):762-773. doi: 10.1111/ene.15635. Epub 2022 Nov 30. |
| Authors: | Hirschwald J, Hofacker J, Duncan S, Walshe M |
| Institution: | Clinical Speech and Language Studies, Trinity College Dublin, Dublin, Ireland hirschwj@tcd.ie.; Clinical Speech and Language Studies, Trinity College Dublin, Dublin, Ireland. | | Journal: | BMJ Evid Based Med. 2023 Apr;28(2):111-118. doi: 10.1136/bmjebm-2022-112082. Epub 2022 Nov 11. |
| Authors: | Feller D, Fox I, Gozzer P, Trentin F, Papola D |
| Institution: | Provincial Agency for Health of the Autonomous Province of Trento, Trento, Italy; Centre of Higher Education for Health Sciences of Trento, Trento, Italy. Electronic address: danielfeller.ft@gmail.com.; WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine, and Movement Science, Section of Psychiatry, University of Verona, Verona, Italy. | | Journal: | Arch Phys Med Rehabil. 2023 Feb;104(2):331-339. doi: 10.1016/j.apmr.2022.07.021. Epub 2022 Aug 27. |
| Authors: | Bucur M, Papagno C |
| Institution: | Center for Mind/Brain Sciences (CIMeC), University of Trento, Trento, Italy. costanza.papagno@unitn.it. | | Journal: | Neuropsychol Rev. 2023 Jun;33(2):307-346. doi: 10.1007/s11065-022-09540-9. Epub 2022 Mar 23. |
| Authors: | Feldman M, Margolesky J |
| Institution: | Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA. | | Journal: | Int J Neurosci. 2023 May;133(5):532-543. doi: 10.1080/00207454.2021.1929217. Epub 2021 Jun 1. |
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What Our Customers Are Saying... "I ordered the MediFocus Guidebook on Parkinson's Disease for my father who has had this condition for about 15 years. It was extremely useful to learn about the medications that are used to treat Parkinson's as well as the side-effects. I had read a lot of articles about Parkinson's on the Internet but they were all very general and vague. Your Guidebook provided excellent and comprehensive information from the medical perspective. Thanks for a very useful resource that is much needed today on the Web."
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Russelsheim, Germany
"I found your Guidebook on Parkinson's to be very informative for me, the patient, and for my husband. I am in the process of changing my medication and the book explained more to me than the doctor attempted to. I am now more aware of what to expect. It also offered valuable advice for the caregiver. Thank you."
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